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結晶著書
分担執筆:基礎生化学実験
6章 細菌遺伝学の方法,pp111-125
東京化学同人,1994,横山茂之編
分担執筆:構造生物学―ポストゲノム時代のタンパク質研究―
第6章 6.3 プリンヌクレオチド生合成系:丸ごと解析,pp227-234
共立出版,2007,倉光成紀,杉山政則編

結晶学術雑誌(論文)
Naoki Nemoto, Gota Kawai and Gen-ichi Sampei
Crystal structure of adenylosuccinate lyase from the thermophilic bacterium Thermus thermophilus HB8. Acta Crystallography Section F, Structural Biology and Crystallization Communication, 79, 278-284 (2023)
https://doi.org/10.1107/s2053230x23009020
Gen-ichi Sampei, Hironori Ishii, Hiroyuki Taka and Gota Kawai
Convergent evolution of nitrogen-adding enzymes in the purine nucleotide biosynthetic pathway, based on structural analysis of adenylosuccinate synthetase (PurA). Journal of General and Applied Microbiology, 69, 109-116 (2023)
https://doi.org/10.2323/jgam.2023.05.002
Gota Kawai, Gen-ichi Sampei, Makoto Nishiyama and Yoshitaka Bessho
Non-coding RNAs and functional RNA elements in Thermus thermophilus. Journal of General and Applied Microbiology, 69, 131-134 (2023)
https://doi.org/10.2323/jgam.2023.05.001
Norifumi Yamamoto, Gen-ichi Sampei and Gota Kawai
Free-Energy Profile Analysis of the Catalytic Reaction of Glycinamide Ribonucleotide Synthetase. Life, 12, 281 (2022)
https://doi.org/10.3390/life12020281
Shibanuma, Y., Nemoto, N., Yamamoto, N., Sampei, G., and Kawai, G.
Crystal structure of adenylate kinase from an extremophilic archaeon Aropyrum pernix with ATP and AMP. Journal of Biochemistry, 168, 223-229 (2020)
Aoba Ogawa, Gen-ichi Sampei and Gota Kawai
Crystal Structure of Flavin Dependent Thymidylate Synthase, Thy1, from Thermus thermophilus having an Extra C Terminal Domain
Acta Crystallography Section F, Structural Biology and Crystallization Communication, 75, 450-454 (2019)
Gota Kawai, Yuri Aoki, Maina Otsu, Naomi Koike, Gen-ichi Sampei
RNomics of Thermus thermophilus HB8 by DNA microarray and next-generation sequencing
Journal of Biochemistry, 162, 423-430 (2017)
Watanabe Y, Yanai H, Kanagawa M, Suzuki S, Tamura S, Okada K, Baba S, Kumasaka T, Agari Y, Chen L, Fu ZQ, Chrzas J, Wang BC, Nakagawa N, Ebihara A, Masui R, Kuramitsu S, Yokoyama S, Sampei G, Kawai G.
Crystal structures of a subunit of the formylglycinamide ribonucleotide amidotransferase, PurS, from Thermus thermophilus, Sulfolobus tokodaii and Methanocaldococcus jannaschii
Acta Crystallography Section F, Structural Biology and Crystallization Communication, 72, 627-635 (2016)
Mayumi Kanagawa, Seiki Baba, Yuzo Watanabe, Noriko Nakagawa, Akio Ebihara, Gen-ichi Sampei and Gota Kawai
Crystal structures and ligand binding of PurM proteins from Thermus thermophilus and Geobacillus kaustophilus
Journal of Biochemistry, 159, 313-321 (2016)
Gen-ichi Sampei, Mayumi Kanagawa, Seiki Baba, Toshiaki Shimasaki, Hiroyuki Taka, Shohei Mitsui, Shinji Fujiwara, Yuki Yanagida, Mayumi Kusano, Sakiko Suzuki, Kayoko Terao, Hiroya Kawai, Yoko Fukai, Noriko Nakagawa, Akio Ebihara, Seiki Kuramitsu, Shigeyuki Yokoyama and Gota Kawai
Structures and reaction mechanisms of the two related enzymes, PurN and PurU
Journal of Biochemistry,154, 569-579 (2013)
Sakiko Suzuki, Hisaaki Yanai, Mayumi Kanagawa, Satoko Tamura, Yuzo Watanabe, Kyotaro Fuse, Seiki Baba, Gen-ichi Sampei and Gota Kawai
Structure of N-formylglycinamide ribonucleotide amidotransferase II (PurL) from Thermus thermophilus HB8
Acta Crystallography Section F, Structural Biology and Crystallization Communications, 68, 14-19 (2012)
Gen-ichi Sampei, Seiki Baba, Mayumi Kanagawa, Hisaaki Yanai, Takeshi Ishii, Hiroya Kawai, Yoko Fukai, Akio Ebihara, Noriko Nakagawa and Gota Kawai
Crystal Structures of Glycinamide Ribonucleotide Synthetase, PurD, from Thermophilic Eubacteria
Journal of Biochemistry, 148, 429-438 (2010)
Kanagawa M., Baba S., Ebihara A., Shinkai A., Hirotsu K., Mega R., Kim K., Kuramitsu S., Sampei G., Kawai G.
Structures of hypoxanthine-guanine phosphoribosyltransferase (TTHA0220) from Thermus thermophilus HB8
Acta Crystallography Section F, Structural Biology and Crystallization Communications, 66, 893-898 (2010)
Gen-ichi Sampei, Nobuhisa Furuya, Keiko Tachibana, Yasuhiro Saitou, Takuji Suzuki, Teruya Komano
Complete genome sequence of the incompatibility group I1 plasmid R64
Plasmid, 64, 92-10 (2010)
Matsuo, E., Sampei, G., Mizobuchi, K., and Ito, K.
The plasmid F OmpP protease, a homologue of OmpT, as a potential obstacle to E. coli -based protein production
FEBS Letter, 461, 6-8 (1999)
Yamamoto, Y., Aiba, H., Baba, T., Hayashi, K., Inada, T., Isono, K., Itoh, T., Kimura, S., Kitagawa, M., Makino, K., Miki, T., Mitsuhashi, N., Mizobuchi, K., Mori, H., Nakade, S., Nakamura, Y., Nashimoto, H., Oshima, T., Oyama, S., Saito, N., Sampei, G., Satoh, Y., Sivasundaram, S., Tagami, H., Takahashi, H., Takeda, J., Takemoto, K., Uehara, K., Wada, C., Yamagata, S., and Horiuchi, T.
Construction of a Contiguous 874-kb Sequence of the Escherichia coli K-12 Genome Corresponding to 50.0-68.8 min on the Linkage Map and Analysis of Its Sequence Features
DNA Research, 4, 91-113, 169-178 (Supplement) (1997)
Itoh, T., Aiba, H., Baba, T., Hayashi, K., Inada, T., Isono, K., Kasai, H., Kimura, S., Kitakawa, M., Kitagawa, M., Makino, K., Miki, T., Mizobuchi, K., Mori, H., Mori, T., Motomura, K., Nakade, S., Nakamura, Y., Nashimoto, H., Nishio, Y., Oshima, T., Saito, N., Sampei, G., Seki, Y., Sivasundaram, S., Tagami, H., Takeda, J., Takemoto, K., Wada, C., Yamamoto, Y., and Horiuchi, T.
A 460-kb DNA Sequence of the Escherichia coli K-12 Genome Corresponding to the 40.1-50.0 min Region on the Linkage Map
DNA Research, 3, 379-392, 441-445 (Supplement) (1996)
Aiba, H., Baba, T., Hayashi, K., Inada, T., Isono, K., Itoh, T., Kasai, H., Kashimoto, K., Kimura, S., Kitagawa, M., Makino, K., Miki, T., Mizobuchi, K., Mori, H., Mori, T., Motomera, K., Nakade, S., Nakamura, Y., Nashimoto, H., Nishio, Y., Oshima, T., Saito, N., Sampei, G., Seki, Y., Sivasundaram, S., Tagami, H., Takeda, J., Takemoto, K.,Takeuchi, Y., Wada, C., Yamamoto, Y., and Horiuchi, T.
A 570-kb DNA Sequence of the Escherichia coli K-12 Genome Corresponding to the 28.0-40.1 min Region on the Linkage Map
DNA Research, 3, 363-377, 435-440 (Supplement) (1996)
Ohshima. T., Aiba, H., Baba, T., Fujita, K., Hayashi, K., Honjo, A., Ikemoto, K., Inada, T., Isono, K., Itoh, T., Kajihara, M., Kanai, K., Kashimoto, K., Kimura, S., Kitakawa, M., Makino, K., Masuda, S., Miki, T., Mizobuchi, K., Mori, H., Motomera, K., Nakamura, Y., Nashimoto, H., Nishio, Y., Saito, N., Sampei, G., Seki, Y., Tagami, H., Takemoto, K., Wada, C., Yamamoto, Y., Yana, M., and Horiuchi, T.
A 718-kb DNA Sequence of the Escherichia coli K-12 Genome Corresponding to the 12.7-28.0 min Region on the Linkage Map
DNA Research, 3, 137-155, 211-223 (Supplement) (1996)
Nagadoi, A., Morikawa, S., Nakamura, H., Enari, M., Kobayashi, K., Yamamoto, H., Sampei, G., Mizobuch,i K., Schumacher, M. A., Brennan, R. G., and Nishimura, Y.
Structural comparison of the free and DNA-bound forms of the purine repressor DNA-binding domain
Structure, 3, 1217-1224 (1995)
Sampei, G., and Mizobuchi, K.
The Organization of the purL Gene Encoding 5'-Phosphoribosyl- formylglycinamide Amidotransferase of Escherichia coli
Journal of Biological Chemistry, 264, 21230-21238 (1989)
Watanabe, W., Sampei, G., Aiba, A., and Mizobuchi, K.
Idetification and Sequence Analysis of Escherichia coli purE and purK Genes Encoding 5'-Phosphoribosyl-5-Amino-4-Imidazole Carboxylase for de novo Purine Biosynthesis
Journal of Bacteriology, 198, 198-204 (1989)
Sampei, G., and Mizobuchi, K.
Nucleotide sequence of the Escherichia coli purF gene encoding amidophosphoribosyl-transferase for de novo purine nucleotide synthesis
Nucleic Acids Research, 16, 8717 (1988)

結晶国際会議プロシーディングス
Gen-ichi Sampei and Gota Kawai
Gene organizations and its regulation in the purine biosynthetic pathway. International Workshop on Neotechnologies for ThermusQ initiative, p115 (2023)
Gen-ichi Sampei and Gota Kawai
Gene organizations and their regulation in the nucleotide biosynthetic pathway. International Workshop on 50th Anniversary of Thermus thermophilus Discovery, p169 (2018)
Maina Otsu, Yuri Aoki, Naomi Koike, Gen-ichi Sampei and Gota Kawai
RNomics of Thermus thermophilus HB8. International Workshop on 50th Anniversary of Thermus thermophilus Discovery, p125 (2018)
Gota Kawai, Seiki Baba, Mayumi Kanagawa, Seiki Kuramitsu, Gen-ichi Sampei
Dissecting enzyme mechanisms in the purine nucleotides biosynthetic pathway
Acta Crystallography, A67, C782 (2011)
Shinnosuke Seki, Atsushi Kijima, Satoshi Kobayashi, and Gen-ichi Sampei
Hierarchical Alignment of RNA Secondary Structures Including Pseudonots
Proc. 15th
International Conference on Genome Informatics, p117 (2004)
Mizobuchi, K., and Sampei, G.
Organization and Diversification of Genomes of the IncF and IncI Plasmids by Shuffling of Functional Modules
Frontier of the Genome Biology of Escherichia coli, p7 (1998)
Kobayashi, S., Yokomori, T., Sampei, G., and Mizobuchi, K.
DNA Implementation of Simple Horn Computation
IEEE International Conference on Evolutionary Computation, pp213-217 (1997)
Nagadoi, A., Nakazawa, K., Morikawa, S., Nakamura, H., Sampei, G., Mizobuchi, K., Yamamoto, H., Schumacher, M. A., Brennan, R. G., and Nishimura, Y.
Conformational changes of purine repressor DNA-binding domain upon complexation with DNA
Nucleic Acids Symp. Ser., 34, 63-64 (1995)
Kawai, G., Takayanagi, M., Hayashi, N., Niimi, T., Sampei, G., Mizobuchi, K., Miyazawa,T., Yokoyama, S., and Watanabe, K.
15N and 13C labeling of Escherichia coli tRNAs toward the NMR analysis
Nucleic Acids Symp. Ser., 27,131-132 (1992)
Sampei, G., Yonetani, Y., Nakamura, K., and Mizobuchi, K.
Regulatory Network Coregulated by PurR/PUR box System
Cold Spring Harbor Meeting on Molecular Genetics of Bacteria and Phages, p176 (1990)

結晶学会発表・シンポジウム等発表(過去5年間)
三瓶 嚴一,河合 剛太:
プリノソームとプリンヌクレオチド生合成系酵素群の進化,第45回日本分子生物学会年会 ワークショップ「代謝系×相分離の新たな挑戦」 (2022.12)
三瓶 嚴一
ヌクレオチド合成系の起源と進化,東京理科大学生物環境イノベーション研究部門・ 公開シンポジウム 〜生物進化の立場から生物環境を考える〜 (2021.8)
佐々木 麗央,三瓶 嚴一
高度好熱菌プリンオペロンに存在するorfの遺伝子破壊と表現型解析,第43回日本分子生物学会年会 (2020.12)
齊藤 有紀,小池 奈緒美,青木 優里,河合 剛太,三瓶 嚴一
高度好熱菌ピリミジンヌクレオチド生合成系オペロンの転写開始点解析,第42回日本分子生物学会年会 (2019.12)
若林 新,河合 剛太,三瓶 嚴一
2種類の高度好熱菌Thermus thermophilus HB8由来PRPP synthetaseの酵素活性,第42回日本分子生物学会年会 (2019.12)
計良 哲巧,河合 剛太,三瓶 嚴一
高度好熱菌Thermus thermophilus HB8由来IMP dehydrogenase (GuaB)の酵素活性特性の評価,第41回日本分子生物学会年会 (2018.11)
青木 優里,小池 奈緒美,齊藤 有紀,三瓶 嚴一,河合 剛太:
NGS解析による高度好熱菌からの新規small non-coding RNAの探索,第41回日本分子生物学会年会 (2018.11)
小池 奈緒美,青木 優里,河合 剛太,三瓶 嚴一
高度好熱菌プリンヌクレオチド生合成系オペロンの転写開始点解析,第41回日本分子生物学会年会 (2018.11)
齊藤 有紀,小池 奈緒美,青木 優里,河合 剛太,三瓶 嚴一
高度好熱菌ピリミジンヌクレオチド生合成系オペロンの転写開始点解析,第41回日本分子生物学会年会 (2018.11)
小川 青葉,三瓶 嚴一,河合 剛太:
Thermus thermophilus 由来チミジル酸合成酵素の立体構造とC末端ドメインの機能の解析,第41回日本分子生物学会年会 (2018.11)
三五 ちはる,三瓶 嚴一,河合 剛太,根本 直樹:
好熱好酸性アーキアSulfolobus tokodaii由来プリンヌクレオチド生合成の酵素FAICAR,第41回日本分子生物学会年会 (2018.11)

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E-mail: gsampei@uec.ac.jp
〒182-8585 東京都調布市調布ヶ丘1-5-1 電気通信大学 大学院情報理工学研究科 基盤理工学専攻 三瓶研究室

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